Easy:
11D. Course of existence (4, 5) Life, * * * * E,
Funny but slightly rude (4) * * * *
22A Large paned opening (7, 6) * * * * u * *, window
Cryptic8A Show tiredness on way back up inside (4) * A * N
11A Hurried to said crag (4) T * R * Tore, Tarn??