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Hi shaneystar, thanks for responding, I think it's all very interesting! You seem to have got your thyroid problem quite late on, although my elder brother has just recently been diagnosed overactive, he's 54. I am female too, 48 years old, I started with mine around the age of 16/17. My mum suffered with overactive thyroid & her mum had a goitre. I have two teenagers, both tested when born ( heel prick ) - negative thank goodness! Have you ever tried glucosamine for your joints? I am hearing very good things about it but haven't yet tried it.