Sqad, I find that sterimar does help mechanically. I am not convinced that it has any effect on swollen tissue, but if any part of the blockage is caused by gunk, especially thick gunk, then it does seem to help to keep the drainage going and is very soothing on soreness....but if the right antibiotic isn't working then I would be going back to the doc but after finishing the course unless its getting markedly worse. I find when I get a sinusitis that I need an antibiotic to clear, (usually I can get rid of it with sterimar and a decongestant plus spicy food) it will take until 3/4 of the course to seean improvement and, because the gunk starts draining as the infection recedes, it feels worse before it feels better.