Medical Question For The Ab Gps

[piggynose]

In what way does aspirin help in a suspected heart attack?
Tia

[Mamyalynne]

It works as an clotting inhibitor,.

[Mamyalynne]

Not qualified, just knew that fact.

[woofgang]

It doesn't help with the attack but may limit damage because it is an anti coagulant

[Sqad]

So it DOES help woofy..

[Jackdaw33]

It thins the blood but for some reason is now out of favour with the medical profession.

[Mamyalynne]

Out of favour as a daily dose Jack but not in the instance posed by the OP.

[woofgang]

PS I have just done a fast google and cannot find any research confirming or refuting this. I did find a couple of american websites suggesting that it "may" help to limit damamge due to a blood clot and that you should chew or crush the aspirin for the fastest effect. My gut feeling is that the clot would have plenty of time to form before the aspirin got into the stomach and thence into the bloodstream. I don't believe it busts clots, only makes the blood less likely to clot. Even the websites that suggest it are clear that the first action should be to get the emergency services out or head off to A and E pronto.

[woofgang]

Sqad, i would say "might" rather than "does"

[sanmac]

And I believe that you have to chew on the aspirin, and not merely swallow it.

[Mamyalynne]

Totally agree that you shouldn't delay in order to find the aspirin, hit triple 9 first.

[woofgang]

yup sanmac, crush or chew so its absorbed faster, again no research though

[calmck]

I think by chewing the aspirin it is absorbed into the blood stream through the vessels in the tongue. Always used to be given as emergency tx for suspected heart attack when I was working

[Peter Pedant]

// Aspirin is effective in reducing the blood clots that are blocking a coronary artery during an acute heart attack. Anyone who has already had a heart attack, or who has an increased risk of having one in the future, should always carry a few non-coated adult aspirins with them.//

works in the acute phase which I have always found surprising. Warfarin doesnt by the way

Low-dose aspirin irreversibly blocks the formation of thromboxane A2 in platelets, producing an inhibitory effect on platelet aggregation during the lifetime of the affected platelet (8–9 days).

PLatelets aggregate. That's what they do. Aspirin zaps a protein that is necessary for this in the platelet. And since they dont have nuclei ( platelets that is silly!) they cant replenish the ( irreversibly acetylated ) protein

well someone asked how it worked

Hey ya wanna know how it unlinks mitochondrial oxidation in Reye's Syndrome? no I didnt think so

[Buenchico]

Sqad would be disappointed if I didn't post a link here ;-)

https://www.nhs.uk/conditions/heart-attack/
(See 'Treating heart attacks')

[woofgang]

apparently not. This is about migraine and glycinated aspirin but apparently neither it, nor ordinary asprin was absorbed in the mouth. https://pubmed.ncbi.nlm.nih.gov/3516407/

[jennyjoan]

//It thins the blood but for some reason is now out of favour with the medical profession.//

My cousin has been on aspirin 5 years now and she has been told it could be leading to other problems for her.

[Jackdaw33]

Apparently the syndrome affects mainly children so aspirin as an anaelgesic is not recommended for them.

[237SJ]

It helps prevent further clotting (by making the platelets slippery)

[piggynose]

So it wouldn't hurt to carry a few aspirin while you're out+ about.
Going to sound stupid now. Are aspirin and paracetomol related? As they both relieve headaches.

[Vagus]

Aspirin and ibruprofen are, but not paracetamol.