Free radicals are highly reactive compounds in the body, which are created during normal metabolic activity or acquired from the environment. They are unstable molecules which take an electron from other cells in your body, causing damage. The biggest effect is aging, but they are also believed to contribute to other degenerative diseases. Antioxidants are supposed to help eliminate the effects of free radicals, but one study I saw showed that OTC supplements did nothing against the free radicals effects.