If you take out an conventional boiler and replace with a combi system often you gain room space because the bulky hot water cylinder is no longer required and is taken away. Also you won't need any roof tanks so potentially it's easier to do a conversion up there.
To be honest if you're letting out your property I wouldn't bother unless a severe lack of space is causing the potential rent to be lowered because if a combi boiler fails there's no back-up, whereas with a conventional boiler there is usually an immersion heater in your hot water cylinder so you can get hot water by another means (i.e. less hassle for the landlord from the tenants!).
You have to also bear in mind that with pipework alterations and a change in airing cupboard size or whatever there is often more work created where skirting boards or cupboards need sorting out or the carpet no longer fits properly so you could end up spending even more than you think.
I doubt it would affect the sale value of the house or flat.