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No best answer has yet been selected by saxo_boi. Once a best answer has been selected, it will be shown here.
For more on marking an answer as the "Best Answer", please visit our FAQ.You can get right-angled drills for this - they can be a bit pricey but you can often hire them.
If what you want to drill is not too heavy-weight then there are right angle chucks around but I broke one quite quickly so you might want to think of them as semi-disposable.
http://www.hgtv.com/hgtv/remodeling/article/0,1797,HGTV_3659_1915206,00.html