anything with five bits: quintuplets for example. Origin: its alchemical! The quintessence was the substance from which everything was derived, and was used as a synonym for the philosophers stone in some texts. They believed in five elements, earth, air fire water and spirit (or other versions of the list) so the quintessence (five essence) was the perfect combination of all five. As for other words, quince (as in the fruit) is probably derived from quint, referring to the five sepals on the base of the fruit.