19 across - His best-known poem included a talking horse, "Mr Ed" (4) - D?R? - Derm, anagram of "Mr Ed" fits, but why?
2 down - Councillor welcomed by a consular agent in the capital of Guinea (5) - A?C?A - I can get Accra (CR abbreviation for councillor A CA for a consular agent), but Accra is the capital of Ghana.