10ac. Retail chain upset as there’s not a single lady looking for All Creatures Great and Small (8) ?I?D???E
13ac. Leaves countless numbers indeed, but not any more ! (10)? E?O???T??
18ac. Give it your best shot as it’s on the bone (10) ??????S?T?
22ac. Famous old tenor from Derry heading for a pretty dour party- in the Maze or Maghaberry (6,2) ????ED UP
3dn. In other words can go in, though not there, if you show you can refrain from the cigs and booze. (9) A?S??????
15dn. Telling the barman how to make a straight gin cocktail. (9) ??????ING
19dn. It looks threatening like an unopened parcel of fodder or cotton. (7) ????FUL