The Desert Inn was a Las Vegas, Nevada hotel/casino that operated from April 24, 1950 to August 28, 2000. It was the fifth resort to open on the Las Vegas Strip. The property included an 18-hole golf course. Locals nicknamed the resort "The D.I."
On April 27, 2000, the resort was purchased by Steve Wynn, who closed it several months later. On October 23, 2001, the main tower was demolished to make room for a megaresort that Wynn planned to build. Originally intended to be named Le R�ve, the new project opened as the Wynn Las Vegas.