“Current glucometers use test strips containing glucose oxidase, an enzyme that reacts to glucose in the blood droplet, and an interface to an electrode inside the meter,” explains Michael Strano, the Charles and Hilda Roddey Associate Professor of Chemical Engineering at MIT. “When the strip is inserted into the meter, the flux of the glucose reaction generates an electrical signal,” he says. “The glucometer is calibrated so the number appearing in its digital readout corresponds to the strength of the electrical current: The more glucose in the sample, the higher the number.”
Hope that helps you.