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Microsatellite marker genes

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shane watson | 09:40 Fri 29th Feb 2008 | Science
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What is microsatellite marker genes can anyone give more information on microsatellite marker genes.
Thanks.
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Microsatellites refer to the short repetitive sequences of DNA that can be employed as markers for the identification of certain genes. For colon cancer, microsatellite marker genes have been identified on chromosome 2 in humans. There is a lot of variability in the sequence of microsatellites.
Early detection of the risk for colon cancer by DNA analysis is a boon for the world is victims of this disease. The suspected individuals can be periodically monitored for the signs and treated appropriately. Unlike many other cancers, the chances of cure for colon cancer are reasonably good.
http://www.healthknow.info/diagnosis_of_geneti c_diseases.asp
Good summary

microsatellite markers show less variability in this cancer - which is kinda odd. How do they affect the disease - no-one knows. And what does the normal micrsatellite DNA do, unknown.

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