Mankak -
"Behold, your house is left unto you desolate" Luke 13: 35.
Jerusalem's house was the temple. Because of their rejection of Christ, after His many offers to them, the Lord Jesus is saying that the temple is left desolate, empty, like a wilderness to them.
(BTW Remember when the Lord had went to the temple and found it to be a house of merchandise and den of thieves)
With all of it's finery and decoration, and being the pride of the city, God's Glory had now left it forever.
Reminds us that we can do all the religious duites etc in the world but it is nothing and meaningless without Christ.
And of course, along the same lines as Cetti's comment, Christ had already forwarned of the temple's physical destruction, to come a number of years later.