Also consider, if looking Manchester way, your girlfriend having to drive or commute after such a long shift, especially as a nurse, even though she might find it easier traffic wise commuting at that time.
Public transport could be a factor depending on wages. With say a train fare and tram on top (far quicker than any of the buses from the centre and can be boarded at the station to Sale) would add up quickly.
Stations on the Bury met (tram) line (eg Prestwich, Whitefield) Oldham/Ashton under Lyne/Rochdale way could mean about a 40-50 min drive to Dewsbury hospital and when the met is up and running from those places (underway but a while for some destinations - Bury on now though) you could get the met into town and out to Sale and some of the Bury services run through to Altrincham (line Sale is on). You can get season tickets cheaper.