Worsley, in Salford, is lovely. Didsbury is nice, lots of young professionals and bars, pubs and some shops and places to eat about.
You are heading out Cheshire way (well, as opposed to main Manchester) with Hale (and Hale Barns) and Bowden and out round Poynton and Prestbury, much more affluent and popular with footballers and such. There are also some nice places round Stockport way such as Bramhall.
The city centre is very popular to live and there are some lovely apartment developments which attract more affluent people. Castlefield has a nice young professional feel to it too with some lovely bars (think posh barbeque outside on summer weekends) and round the canals.