I have a DVD (language course) which used to work when I had earlier versions of Windows, but now I have W10 might be the reason that when I try to open it I get the message, "Unsupported Configuration - your screen resolution is not supported. Try using a different setting"
If the software on the DVD doesn't like your screen resolution, try altering it.
Right-click on your desktop and select 'Display settings'. Change the resolution to something which older software might have been designed for (such as 1280 x 1024), click 'Apply' and try to load the software again. [NB: Don't panic if your screen goes totally blank for a second or two after selecting 'Apply'. It's perfectly normal. You've not broken anything!]