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Hooray! Eventually solved my problem with iTunes not opening.
Following member's advise I tried updating .Net Framework but couldn't get it to complete the update. Similar with Active X.
So I looked into what Windows updates were available and found that although I appeared to have had regular updates there were many missing. 185 it seems!!
I can't tell you how many hours that took to download and then further hours configuring the Windows updates. However it was worth it as everything now works and I've got my music back.
Thanks for all your suggestions.