Here's a link from
BBWCHATT's post re: transportation.
Her link has already covered the highlights, especailly the San Diego Zoo in Blaboa Park... don't miss it. It
is at least a full day, better if you have a couple of days.
For some side trips, be sure to visit Hamm's Light House... a restaurant just across the highway as you exit Lindbergh Field (San Diego Airport). It's at the end of a man-made island, ahs the best Mexican Food in town as well as the finest Margarita's. a beautiful setting at sundown. Seen here:
http://www.tomhamslighthouse.com/index.html
additionally, on the same island (Harbor Island) a good seafood restaurant is in a marina. Seen here:
http://www.boathouserestaurant.com/pages/main_ frameset.htm
Don't miss
The Star of India, seen here:
http://www.beachcalifornia.com/starof.html and it's right in the middle of excellet sea food restaurants as well...
And finally, take some extra effort and see Point Loma Light... the setting is magificent, especially at sundown as well.. Here:
http://www.beachcalifornia.com/light.html
Welcome to my favorite city in the U.S.!