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Thanks again IAP. When I see the doctor again I'm going to discuss this with her (young, Spanish but good English), and I hope she'll agree to my having six months off them. I'd really like to have a blood test done after six months, rather than wait the normal 12 - if the results are a disaster I don't want to have to 'fess up, and anyway it will probably worry me, wondering what's going to happen! Plus, if the liver test comes back OK she'll be giving me a 12 month prescription for all my meds, so I may as well try and sort it from the start.