That covers a lot of possible faults!
I would try to get the photos (and any other precious data) off the drive first, but - depending on the symptoms - wouldn't totally give up on the machine yet.
When you turn your computer on, what happens? Does it start up at all? Do you have any recovery or Windows discs? If you tap the F8 key during boot, can you get into "safe mode"?
The hard drive could well be shot, but it could all sorts of things including: a loose connector, corrupt boot sector, or virus (or many more). If you post the exact symptoms on here, someone may be able to help.