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No best answer has yet been selected by Erdinger. Once a best answer has been selected, it will be shown here.
For more on marking an answer as the "Best Answer", please visit our FAQ.Just to add to clanad's excellent answer;
V1 and V2 are calculated before take-off and depend on such variables as atmospheric conditions and aircraft load.
V1 also factors in the length of the runway, as V1 is 'the point of no return' whereby the pilot must continue with take-off even if an engine fails. (Aircraft have to be capable of taking off with one engine down as part of their certification.)
Any attempt to abort take-off once V1 has been attained will result in the aircraft running out of runway before it has had time to stop. The consequences of overshooting the runway at a high rate of knots are not very pleasant!
The next time you fly, listen out for these 'callouts' (as they are known) from the Pilot Not Flying. Once you hear 'V1' you know that the only way is up !!