The pain of shingles can be really severe and debilitating and sge has my sympathies. It can affect the chest (over the ribs) but more seriously the side of the face and may involve the cornea. I have no idea which part of the body has been affected with your wife. Pain relief: can be extremely difficult and I suppose rhat she has taken Paracetamol, co-codemol and the usual painkillers. In extrem cases morphine or morphine like derivatives may be required or even regional nerve block at your local Pain Clinic. There have been reports that Amytryptiline or nortryptiline, both antidepressants some 40 yrs old. if taken early enough can relieve the pain. That is the good news, the bad news is that the pain after the rash has disappeared can last up to 6months.