Reform Gaining Huge Numbers Of Votes...
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For more on marking an answer as the "Best Answer", please visit our FAQ.This will almost certainly offend some of our more enlightened readers but I should stick to "Dear Sir". As you say, "Dear Sir or Madam" does sound a bit clumsy. Dear Sir is certainly presumptuous, but then I cannot get on with the "Chair" of a committee. Chairman, I'm afraid, until I know the gender. A chair is something the chairman or chairwoman sits upon.
Somebody needs to develop a gender-neutral vocabulary for these sort of things otherwise the World and her Husband will always be asking these questions!
If you know you are writing to an individual female, but don't know the name you would address them as Dear Madam, if you know you are writing to an individual man and you don't know his name you would address them as Dear Sir. It is generally acceptable to use Dear Sir or Madam if you don't know the sex of the individual, but if you are writing to an organisation in general and you don't know if it is a man or a woman (i.e. writing to whole departments) then you would address the organisation as Dear Sirs. Alternatively just write 'To whom it may concern'.
In all instances you would use Yours faithfully.