Lipids

[pwrfid]

Hi everybody, I am reading a book on Physiology. I have gathered that Lipids are digested and eventually transported through the lymphatic system eventually being drained off into the bloodstream. However, they travel in the bloodstream as lipoproteins. Hence, I would like to know where do the lipids combine with proteins and what is the process that determines whether lipids are transported as HDL (High density lipoproteins) or LDLs ?

I sincerely hope you could enlighten me in this regard.
Thanks

[Clanad]

I see you've not received a reply... rather simply put, the lipids become lipoproteins in the liver.  The determination of ration between the LDL (bad) and HDL (good) are primarlily determined by two factors... diet and genetics.  The process of producing each one within the liver, however, is a complex mechanism for which I have no answer...

[estie]

Dietary lipids are incorporated into lipoproteins chylomicrons) inside the intestinal cells, BEFORE they enter the lymph. Endogenous cholesterol and triglycerides are incorporated into lipoproteins (VLDL/LDL) in the liver. VLDL/LDL deliver endogenous triglycerides and cholesterol to the tissues of your body. HDL is synthesized with no insides, just some proteins and a phospholipid-like shell. As it circulates, it fills up with cholesterol from tissues and delivers the cholesterol to the liver (it's the reverse of LDL).