News1 min ago
Sqad - statins again
14 Answers
As you may remember Sqad, I am on simvastatin. There was an article in today's Mail which I have copied below. But the last paragraph on Statins (about being fat soluble) is to me just gobbledegook. Does it mean that simvastatins are harmful - or not ? I just can't understand it - perhaps you could explain this paragraph to me :
http://www.dailymail....lness-causes-fix.html
http://www.dailymail....lness-causes-fix.html
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\\The more fat-soluble the statin (which means it passes through cell membranes quickly and hangs around in the body’s fat continuing to have an effect), the greater propensity it has to cross the barrier that protects the brain from any poisons or toxins that may be in the blood. Simvastatin is the most fat-soluble of the statins.\\\
Honest smurfy......not a bloody clue.....I have read it a dozen times.
Lazygun or slaney will do a better job than me.
Bottom line......34,000 patients and "some" had problems....medical term for "maybe."
Honest smurfy......not a bloody clue.....I have read it a dozen times.
Lazygun or slaney will do a better job than me.
Bottom line......34,000 patients and "some" had problems....medical term for "maybe."
Well, it seems that Simvastin takes a ride on the back of fat and crosses the blood brain/ barrier into the brain, protecting the brain from toxins which may cause memory loss and hence is a good thing.
BUT..how can bloody great fat globules filled with Simvastin cross the blood brain barrier?
This sort of reporting brings the medical profession into disrepute in my opinion.
Where are you LAZYGUN?
BUT..how can bloody great fat globules filled with Simvastin cross the blood brain barrier?
This sort of reporting brings the medical profession into disrepute in my opinion.
Where are you LAZYGUN?
I got put on statins a few years ago.
After some months I got pains in my arms. A differnt doctor said "that'll be the statins, they often cause pains" and took me off them.
Last week I saw yet another doctor, who said "I think I'll put you on statins." (I did tell her what the last one said.)
Conclusion: if the doctors don't bleeping know, how am I supposed to?
After some months I got pains in my arms. A differnt doctor said "that'll be the statins, they often cause pains" and took me off them.
Last week I saw yet another doctor, who said "I think I'll put you on statins." (I did tell her what the last one said.)
Conclusion: if the doctors don't bleeping know, how am I supposed to?
I was on Simvastatin, memory problems were horrendous, worst part OH & I shopping in Gloucester, he stopped to talk to a man, they chatted and included me in conversation, I had not got a clue who he was. After a few moments I realised his voice was familiar, he was husband of my daughters best friend, they have been to our house on numerous occasions, we all spend Christmas Day together, their kids call me Nana. I found the whole thing so distressing I came off the statins. Still suffer losing words and what I did yesterday or 2 /3 days prior.
Simvastatin may or may not cross the blood brain barrier but this doesn't prove that it causes harm.
This is a link to the original Cochrane database article which was looking at primary prevention, that is, drugs given to prevent disease in those who have none.
I can't see anything about side effects or memory loss.
http://summaries.coch...ardiovascular-disease
It is further discussed here
http://www.nhs.uk/new...n-drugs-examined.aspx
Not my area of expertise, but I'm interested to read up about the subject as both sons think I should be on a statin for primary prevention because of family history, but I 'm resisting - they listen to cardiologists too much!
The moral is best not to rely on The Daily Mail for medical advice!
This is a link to the original Cochrane database article which was looking at primary prevention, that is, drugs given to prevent disease in those who have none.
I can't see anything about side effects or memory loss.
http://summaries.coch...ardiovascular-disease
It is further discussed here
http://www.nhs.uk/new...n-drugs-examined.aspx
Not my area of expertise, but I'm interested to read up about the subject as both sons think I should be on a statin for primary prevention because of family history, but I 'm resisting - they listen to cardiologists too much!
The moral is best not to rely on The Daily Mail for medical advice!
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