A large and involved subject bibblebub
\\\\Beta Blockers Don't Work (Apparently)\\
Too simple a heading.
I am not an academic.
I am not a Cardiologist
But here are my thoughts.....depending upon the reason for taking betablockers.
How do beta blockers compare in hypertension?
Evidence is mixed for the long-term use of beta blockers; they are generally less effective than diuretics and no better than placebo in reducing cardiovascular events such as stroke. The exception is one large trial that found that metoprolol was better than a thiazide diuretic in reducing all-cause mortality.
How do beta blockers compare in angina?
In the short term, comparisons of several beta blockers in patients with chronic stable angina have shown that they have similar effects on increasing exercise tolerance and reducing the frequency of angina attacks.
How do beta blockers compare in patients who recently had a coronary artery bypass graft (CABG)?
The long-term use of a beta blocker after CABG does not reduce the risk of death. Other outcomes are also not improved, for
How do beta blockers compare in patients who recently had a heart attack?
Depends upon which bêta blocker.
How do beta blockers compare in heart failure?
Compared to placebo, in patients with mild to moderate heart failure, carvedilol, metoprolol succinate, and bisoprolol reduce the risk of death.
In patients with severe heart failure, both carvedilol and metoprolol succinate reduce mortality, but evidence is stronger for carvedilol. [full review]
How do beta blockers compare in patients who recently had a coronary artery bypass graft (CABG)?
The long-term use of a beta blocker after CABG does not reduce the risk of death. Other outcomes are also not improved, for
How do beta blockers compare in patients who recently had a heart attack?
Depends upon which bêta blocker.
How do beta blockers compare in heart failure?
Compared to placebo, in patients with mild to moderate heart failure, carvedilol, metoprolol succinate, and bisoprolol reduce the risk of death.
In patients with severe heart failure, both carvedilol and metoprolol succinate reduce mortality, but evidence is stronger for carvedilol. [full review]
So really ...horses for courses.......depending upon what you expect from your betablocker.
I look forward to the analysis of LazyGun