You're right to have concern about the effects of many spin cycles. Lots of low-level vibration could lead to damage but it depends entirely on the build of the house and the running of the machine. If you've got a well-balanced machine in a solidly built house it should be fine. The bigger thing to plan for is what will happen when (not if because it always happens at some point) the machine has a flood. What kind of ceiling damage might happen, how easy to put right etc.
Also, noise transferring along joists when on spin - might you get annoyed at that, and is there any way of testing it out before you plumb the machine in?
If the machine isn't to be on view, you could do something like put a couple of layers of old carpet down underneath it. This might dampen vibrations and noise, and also act as a bit of a spong if there was a spillage.