nearly there - thanks for previous answers
1D - whither the doctor journeyed, though disdainful of its inhabitants (8) I have H???????
3D - 'there was a looking for comfort rather than ___ ' (6) I have F?????
8D - messenger goes to see ? quite the contrary (6) I haveN?N?I?
11A - thin 14 could be characteristic (8) I have ??H???N?