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Don't Take Ibuprofen For Coronavirus
18 Answers
In today's Guardian ...apparently it can aggravate symptoms and suppress inflammation which is part of the body's defence mechanism.
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The article says, 'Public Health England said there was currently insufficient information on ibuprofen use and Covid-19 to advise people to stop using ibuprofen. “Currently there is no published scientific evidence that ibuprofen increases the risk of catching Covid-19 or makes the illness worse. There is also no conclusive evidence that taking ibuprofen is harmful for other respiratory infections,” it said in a statement.
“Most people with Covid-19 will have a mild illness and some people may need to take medicines, such as paracetamol or ibuprofen, to help with raised temperature, headache and other pains; always follow the instructions on the label if you do take these medicines and do not exceed the stated dose.
“Patients who have been prescribed NSAIDs for long-term health problems should continue to take them as directed by their healthcare professional,” the statement added.'
I think we need to be careful about contradicting the current official guidance.
“Most people with Covid-19 will have a mild illness and some people may need to take medicines, such as paracetamol or ibuprofen, to help with raised temperature, headache and other pains; always follow the instructions on the label if you do take these medicines and do not exceed the stated dose.
“Patients who have been prescribed NSAIDs for long-term health problems should continue to take them as directed by their healthcare professional,” the statement added.'
I think we need to be careful about contradicting the current official guidance.
it is too early to tell
for a variety of reasons - the data is not strong ( low numbers)
and - it is a non prescrip med so people may not have been asked
and it is confounded by other drugs ( of which steroids is one - which I have to say I wouldnt use ever)
observation thrown up by case series such as these may idenfy false leads
it is mainly being old, and male and faving heart disease ( surprisingly not lung disease)
for a variety of reasons - the data is not strong ( low numbers)
and - it is a non prescrip med so people may not have been asked
and it is confounded by other drugs ( of which steroids is one - which I have to say I wouldnt use ever)
observation thrown up by case series such as these may idenfy false leads
it is mainly being old, and male and faving heart disease ( surprisingly not lung disease)
I understand that it’s important NOT to suppress the fever, & allow it to run its course.
Julius Wagner won his Nobel Prize for Medicine in 1926 by curing tertiary syphilis by infecting them with malaria which caused fever. Once the fever had cured the syphilis it was comparatively easy to cure the malaria.
Julius Wagner won his Nobel Prize for Medicine in 1926 by curing tertiary syphilis by infecting them with malaria which caused fever. Once the fever had cured the syphilis it was comparatively easy to cure the malaria.
Corby...the article also says...
" “I would advise against that,” said Prof Ian Jones, a virologist at the University of Reading. “There’s good scientific evidence for ibuprofen aggravating the condition or prolonging it. That recommendation needs to be updated.”
Paul Little, a professor of primary care research at the University of Southampton, said: “The general feeling is that the French advice is fairly sensible. There is now a sizeable literature from case control studies in several countries that prolonged illness or the complications of respiratory infections may be more common when non-steroidal anti-inflammatories [NSAIDs] are used.”
A trial by Little and his colleagues, published in the BMJ, found patients with respiratory infections such as coughs, colds and sore throats who were prescribed ibuprofen rather than paracetamol by their GP were more likely to subsequently suffer severe illness or complications. Several other studies have linked anti-inflammatory drugs to worsened pneumonia.
Little said this could be because inflammation is part of the body’s natural response to infection. “If you’re suppressing that natural response, you’re likely inhibiting your body’s ability to fight off infection,” he said. "
" “I would advise against that,” said Prof Ian Jones, a virologist at the University of Reading. “There’s good scientific evidence for ibuprofen aggravating the condition or prolonging it. That recommendation needs to be updated.”
Paul Little, a professor of primary care research at the University of Southampton, said: “The general feeling is that the French advice is fairly sensible. There is now a sizeable literature from case control studies in several countries that prolonged illness or the complications of respiratory infections may be more common when non-steroidal anti-inflammatories [NSAIDs] are used.”
A trial by Little and his colleagues, published in the BMJ, found patients with respiratory infections such as coughs, colds and sore throats who were prescribed ibuprofen rather than paracetamol by their GP were more likely to subsequently suffer severe illness or complications. Several other studies have linked anti-inflammatory drugs to worsened pneumonia.
Little said this could be because inflammation is part of the body’s natural response to infection. “If you’re suppressing that natural response, you’re likely inhibiting your body’s ability to fight off infection,” he said. "
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