Assuming you mean a CBR600, I have owned both. They are not really aiming for the same market, so one is not really better than the other, they are both the market leaders in their segment. The VFR is a sports tourer, whilst the CBR is more of a sportsbike, although of all the 600s it is the most versatile, as it is relativly comfortable for long distances, and can carry a pillion reasonably well. They both have a reputation for great reliability. There is a total sports version of the CBR now, called the (CBR600RR, as oposed to the normal one, the CBR600F). The CBR is the best selling middleweight sportsbike, and has been for ages, which means they must be good I guess, but they are also very very common. I prefered the VFR, as its greater capacity engine allowed more relaxed riding, at lower revs for a given speed, they handle well on the road, although they would loose out to more sporty tackle on a trackday. VFRs generally have better build quality than just about any other bike, they really are superb, but then again, they aint cheap! The latest incarnation of the VFR has gone up in capacity to 900cc, and has V-Tec, like the Honda cars, but I gather this is a bit of an aquired taste on a bike, they also have pointless, (IMO) linked brakes, so I doubt I will ever buy one again. For me, and many other people, a late VFR750 is the classic 'do it all' bike. Other bikes are faster, or more sporty, or better at touring, but nothing else can do all this so well.