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Prudie...I wasn't aware that there was a maximum number of anti-smoking threads allowed !
If you are looking for 100% proof, than that may not be possible. After all, 100% of smokers don't die from lung cancer do they ? But who would doubt now, that there isn't a proven link with smoking and ill-health ?
Even FOREST, the industry-funded pressure group in favour of smoking, have long ago stopped trying to disprove the link. But they used to deny it.