Bottom left corner stumped me
17a Possibly Reg thinks of a red card(4,2,6) ---g -- -e-r-s ( ? of hearts)?
16d Keeping up an empty compartment (6) no letters
19d Nelson held her in high esteem, maybe! (4) no letters
18d Publication for children (5) no letters (comic)?
22a New version of a decent love story (8) 5th letter is D I think
14a An artist who may be other things to woman (6) -t-h-r