1a) Lay hold of girl in front of gate (5) G????
8a) A thin strip of plastic covering top of nose is at an angle (6) ?S????
2d) Take advantage of girl meeting the Italian (5) ????L
3d) Powerful drug needed at medical centre (6) ?O??N?
12d) Strange inaccessible place by the sound of it (5) E?R?E