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[mightyquin]

14A Dagger splits blouse(6) O ? E ? ? ?
18A Reptile beginning to progress in land (8) ? ? R ? A ? ? ?
4D Last antidote dries out (13) D ? S ? R ? E ? ? ? T? D
15D Regular college class (7) ? ? ? ? O ? M

[Neveracrossword]

14 Obelus, anagram
18 Terrapin
15 Uniform

[Mamyalynne]

18 Terrapin

[Neveracrossword]

4.Disorientated?

[Mamyalynne]

4 Disorientated

[Calibax]

4d Disorientated (if it's LOST)

[Lie-in King]

14a Obelus (dagger; printing mark) - anag 'blouse'
18a Terrapin - 'p(rogress)' (beginning, in) 'terrain'
4d Disorientated - anag 'antidote dries' (if the clue reads "lOst..."?)
15d Uni-form

[Neveracrossword]

I saw Disorientated as the anagram of 'antidote dries' - having Lost for the first word makes sense of it all.