The instruction appears confusing to me also. With a direct HOT WATER system, the water in the hot water cylinder has previously been through the boiler to get hot. This contrasts with an indirect hot water system, where a heat exchanger coil in the cylinder supplies the energy to heat up the water in the cylinder, and the water in the boiler just goes round and round, never getting out. The same water is invariably used to heat the radiators. I am sure you know this, and such water normally has inhibitor in it to prevent the inside of the rads (mild steel) corroding with black magnetite. I think your TR is mild steel, and if so it would be perfectly suitable to substitute for the existing rad, with inhibitor. What I think the instruction is trying to warn you against is fitting the TR in a direct hot water system. In such an arrangement, the TR forms part of the hot water system and the water flowing through the TR eventually emerges from a hot tap. In this arrangement, the TR must be made from stainless steel to stop the inside corroding. (The advantage of such a set-up is that you can run the TR in the summer without running the rest of the CH). But I accept that's not what the note appears to say.