Yet another suggestion:
After venting any air from the system have the heating on (24 hours on any timer, electricity on, boiler on, boiler thermostat up past mid-range, etc.), any room thermostat turned to max, and all radiators but one turned off. Trace heating up of pipes as accessibility allows and then expect the one radiator to warm up. Don't be impatient, circulation may be poor but if the radiator does not heat up within half an hour there is likely to be some fundamental (but not insoluble) problem with the system. Repeat with the other radiator, then finally try both radiators with the rest still turned off.
All the above assumes that the rest of the system heats up satisfactorily and there is not a separate zone valve for the radiators in question and that the boiler and pump work during the above test.
If both radiators warm up satisfactorily during the test (and the others normally do also) but still won't when the others are on then it is likely that you need to re-balance the system.
The procedure could be as follows: Assuming there are downstream (outlet) valves on the upstairs radiators, then open these completely and, with the whole of the system operating (all radiators on full) and everything warmed up, close these outlet valves down gently step by step over a good bit of time until you find the radiator(s) are no longer as warm as they were before. This is the first step - refine (open or close each one) as you feel necessary on the same principle. What you are aiming for is for the water flow to have equal resistance on its way to each and every radiator in the house, giving every one of them an equal chance at getting hot.
Are you new to this system, is it possible the previous users simply did not believe in warmth for these radiators/room(s) and thus the radiators are actually turned off on the outlet side to ensure cold conditions (possibly leading to sedimentation in lines if you have now opened the valves up) ?