Yes I gained 4-5 lbs after taking Mycrogynon because it made me hungry, so I ate more. It also gave me mood swings that got worse, so I switched to Mercilon (also a combined pill), which was fine and I'd recommend (and is also supposed to make you 3lbs lighter after taking it for a year?! Though when you've gained weight from another pill it's kind of too late!). I'd second what's been said above, everyone is different and sometimes you have to switch pills a few times before you get it right, but combined pills are over 99% effective so worth persevering.