Organ donation question

[Wrongn3mber]

I was watching or reading something the other day and i thought of this question so no real purpose except a curious mind.
When someone donates an organ the organ recipient has to take ant rejection drugs. What would happen if a father donated a kidney to his son for lets say 10 years and the son passed away could the organ be given back to the father, and if so would the father then have to start taking anti rejection drugs or would his body accept the organ as his own? One more question does the dna or cells change in the organ from the original owner to the recipients in any way, even a few cells?

[bednobs]

that is a really good question that i don't know the answer to.
i know if you have a bone marrow transplant you change blood groups to that of the donor,but that's slightly different.
If i had to guess i would say the organ remains with the DNA of the original donor but who knows?

[Sqad]

LOL give me time on that one....LOL

[wolf63]

sqad is off to take a couple of ibuprofen :-)

I thought that I was the only one who thought up this type of question. ;-)

[Old_Geezer]

http://www.theanswerb.../Question1050298.html

[rowanwitch]

I've put what little I know on the science post

[Sqad]

I have given this much thought and i feel that the answer, on balance is yes it can, but would it function for very long is the imponderable.

After 10 years, due to local infiltration of lymphocytes and T cells (part of the immune system) which may well have be suppressed and lying "dead" in the transplanted kidney making that kidney..."unsaleable...second hand"
There also may well be technical problems due to fibrosis and scarring making the removal difficult.

Now if Dad had the same blood group as son, then, although anti-rejection drugs may well be necessary for other anti bodies (intra nuclear) the re-transplant could take place........but hey! it is already passed it'e sell buy date so it would almost certainly be useless.

Best i can do ......;-)

[Wrongn3mber]

Thanks for the Some great and informative answers. Sqad can t-cells lay dormant?