you got to laugh!! .... you have ... or you'd cry
read the manual
http://www.lacie.com/download/manual/um_deskto pharddisk1TB_usb_en.pdf
by the sound of it everything you need is on the drive
http://www.lacie.com/us/support/support_manife st.htm?id=10283
the main points are connect the cable to the unit
switch it on.... connect to the PC
looking at all the comments ... difficult to crit any of them
HOWEVER I notice you say C and E plus cd
I guess you created the second partition after the install
I know this won't be as easy as it sounds ....
my personal pref is to reletter my drives (it's a server thing)
so that optical drives use W: (for writeable) and X:
then C: is the active primary drive ... and D: is always the first logical.
if you've installed progs to E: things can get complicated.
anyhow ... I have had problems with new USB initialising and stealing a the first letter after a gap .... once there they won't move.
try shifting the drives to that all the hdd partitions are sequential ... and the cd/dvds are at the last positions (you can always shift them back)