This PC, a Toshiba 'satellite' using Windows 8, has the annoying habit of the cursor freezing on one spot and refusing to budge. What's the cure, short of turning the whole thing off and hoping the cursor moves on restart?
One thing that did occur to me. If you go to the "system" screen (control panel, system, system) you could delete the mouse drivers and then your PC should detect new hardware and reinstall them again. If it doesn't immediately you could unplug then replug the mouse, or worst comes to worst, start a 'search for new hardware'. Might also pay you to check on the web that you have the latest (Win 8 compatible) drivers for it.